The pharmacologic properties of olive oil, the olive fruit, and its leaves have been recognized as important components of medicine and a healthy diet because of their phenolic content. Oleuropein, specifically, is the most prominent phenolic compound, and very abundant in the young olive fruit, lending to its extensive pharmacologic uses for many different health benefits.

• Antioxidant – increases the ability of LDL to resist oxidation, reducing plasma levels of total, free, and esterified cholesterol

• Anti-inflammatory – reduces inflammation by inhibiting lypoxygensase activity and the production of leukotriene

• Anti-hypertensive – lowers both diastolic and systolic blood pressures

• Anti-atherogenic – reduces atherosclerosis by decreasing membrane lipid peroxidation

• Anti-cancer – inhibits growth of cancer cells, especially in some glioblastomas, renal cell carcinomas, breast cancers (esp. HER2+), malignant melanomas, colorectal adenocarcinoma, soft tissue sarcomas, and bladder carcinomas

• Antimicrobial – works well against gram negative and gram-positive bacteria, as well as Mycoplasma; Staphylococcus aureus B, Salmonella enteritidis, Bacillus cereus, Klebsiella pneumoniae, Escherichia coli, Campylobacter jejuni, Helicobacter pylori, and methicillin-resistant Staphylococcus aureus (MRSA)

• Antiviral – works well with herpes, EBV (mononucleosis), viral hepatitis, rotavirus, bovine rhinovirus, canine parvovirus, and feline leukemia virus, respiratory syncytial virus (RSV), para-influenza type 3 virus

• Anti-aging – extends the life of fibroblasts, which secrete collagen proteins, which maintains the structural framework of tissues

• Skin protectant – acts as an antioxidant to the skin, scavenging free radicals which works great on UVB-induced skin damage, preventing skin cancer formation (carcinogenesis), and inhibiting tumor growth

• Neuro-protective – decreases amyloid β (Aβ) aggregation, which is inherent to Alzheimer’s disease​and decreases oxidative damage in the brain most affected by Parkinson’s Disease, aids in repairing damage done by many neurodegenerative diseases

• Anti-hyperglycemic – aids in blood sugar control and levels

Oleurapien is given in an IV form, combined with saline over 90 minutes. It may be given up to 5 days a week.

Some drug interactions may include blood pressure medications because it lowers blood pressure, insulin, or other diabetic medications, because it can lower blood sugar, and certain chemotherapy drugs due to its antioxidant properties.

Potential Side Effects following an Oleurapein infusion include a herxheimers reaction (body aches, headache, joint/muscle pains, sore throat, sweating, fever, vaginal discomfort), dizziness, hypoglycemia. Please tell the IV staff if you are on any BP meds or diabetic medications before your infusion. Your vital signs, including blood pressure should be taken before every infusion. It is also a good idea to come in having already eaten something and well hydrated before each infusion.

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