EBOO Therapy at Florida Integrative Medical Center

One of the nation's earliest and most experienced EBOO providers.

Advanced physician-supervised wellness therapy integrated into personalized care plans.

What Is EBOO Therapy? Understanding Extracorporeal Blood Oxygenation and Ozonation

As interest in proactive wellness and personalized healthcare continues to grow, many patients are exploring advanced therapies that may complement a comprehensive health and wellness program. One therapy gaining attention in integrative and functional medicine settings is EBOO, which stands for Extracorporeal Blood Oxygenation and Ozonation.

EBOO is a physician-supervised procedure that involves circulating blood outside the body through a specialized filtration and oxygenation system before returning it to the bloodstream. The process may also incorporate medical-grade ozone according to established protocols and practitioner discretion.

While EBOO has been utilized internationally for many years, it remains relatively unfamiliar to many patients in the United States. Understanding what the therapy is—and what it is not—can help individuals make informed decisions about whether it may be appropriate as part of their overall wellness plan.

Why Patients Explore EBOO Therapy

People choose to learn more about EBOO therapy for many different reasons. Some are focused on optimizing their overall health, vitality, and healthy aging, while others are searching for additional wellness options after living with persistent symptoms or complex health challenges.

At Florida Integrative Medical Center, EBOO is not viewed as a stand-alone therapy. Instead, it may be recommended as one component of a personalized, physician-directed care plan developed after a comprehensive evaluation of each patient's medical history, current health concerns, laboratory findings, and wellness goals.

Who May Explore EBOO Therapy?

✓ Individuals interested in proactive wellness

✓ Those seeking healthy aging support

✓ Patients pursuing an integrative approach to health

✓ Individuals with complex or long-standing health histories

✓ People looking for physician-guided wellness strategies

✓ Patients seeking to optimize vitality and resilience

Patients who inquire about EBOO often have a variety of health objectives, including supporting:

  • Healthy circulation and oxygen utilization
  • Overall vitality and energy
  • Recovery and resilience
  • Healthy inflammatory balance
  • Immune system wellness
  • Cardiovascular wellness
  • Healthy aging and longevity
  • General wellness and quality of life

Many individuals seeking integrative care also come to FLIMC with complex or long-standing health histories. These may include concerns related to chronic fatigue, brain fog, mold exposure, Lyme disease and other tick-borne illnesses, autoimmune conditions, or cancer support. While EBOO may be considered as part of a broader integrative wellness strategy, every recommendation is individualized and based on each patient's unique clinical presentation.

Because no two patients are alike, treatment recommendations are never based on a diagnosis alone. Every patient receives a comprehensive evaluation to determine whether EBOO—or another therapy—may be appropriate as part of their personalized wellness plan.

Experience Matters

Dr. John Monhollon recognized the potential of EBOO long before it became widely available in the United States. As one of the earliest physicians to incorporate EBOO into clinical practice, he helped pioneer its use in an integrative medicine setting.

Today, FLIMC has performed thousands of EBOO procedures for patients traveling from across Florida, throughout the United States, and internationally.

That combination of early adoption, extensive clinical experience, and personalized physician oversight makes FLIMC one of the country's most experienced EBOO providers.

What Does EBOO Stand For?

EBOO stands for:

Extracorporeal Blood Oxygenation and Ozonation

  • Extracorporeal means "outside the body."
  • Blood oxygenation refers to exposing blood to oxygen.
  • Ozonation refers to the controlled use of medical-grade ozone within the procedure.

The therapy utilizes specialized equipment designed to circulate blood through a closed-loop system where it may be filtered, oxygenated, and exposed to ozone before being returned to the body.

The procedure is performed under medical supervision and is distinct from standard intravenous therapies because blood is temporarily circulated through an external treatment system.

EBOO illustrtion

How Does EBOO Work?

During an EBOO session, blood is withdrawn through intravenous access and circulated through a specialized extracorporeal system before being returned to the body. The procedure takes place within a closed-loop circuit designed specifically for blood oxygenation, ozonation, and filtration.

As blood moves through the system, it may be:

  • Exposed to medical-grade oxygen
  • Exposed to carefully controlled concentrations of medical-grade ozone according to physician-directed protocols
  • Passed through specialized filtration components incorporated into the EBOO system
  • Continuously circulated and returned to the bloodstream throughout the session

Unlike many other ozone-based procedures that treat smaller volumes of blood intermittently, EBOO allows a significant volume of blood to circulate through the system during a single treatment session. The amount of blood processed and treatment duration may vary based on the patient's individualized care plan.

How EBOO works

What Makes EBOO Different?

Several forms of ozone-based therapies are used within integrative medicine, including Major Autohemotherapy (MAH), Ultraviolet Blood Irradiation (UBI), and multi-pass ozone protocols.

EBOO differs because it continuously circulates blood through an extracorporeal filtration and oxygenation system throughout the treatment session rather than treating smaller blood volumes in multiple cycles.

Because of this continuous circulation process, EBOO is often viewed by practitioners as one of the more technologically advanced ozone-based procedures available in integrative medicine settings.

Patients interested in ozone therapies are encouraged to discuss the various options with their healthcare provider to determine which approach may be most appropriate for their individual health goals.

I discovered FLIMC while researching SOT treatments for Lyme. The person who attended me was kind, patient, and spent over 20 minutes discussing my situation and explaining the therapy. Unlike other places that charged high fees just for a consultation, FLIMC made me feel supported from the start. 

Eventually, I chose to do Ozone EBOO therapy along with exosomes. These cutting-edge treatments are offered at only a few clinics nationwide.

Everyone at FLIMC is friendly, caring, and focused on safety. I’m still undergoing treatment, but I highly encourage anyone with complex chronic illnesses to reach out to Florida Integrative Medical Center. 

Prince M
EBOO at FLIMC Sarasota

Why Do Patients Explore EBOO Therapy?

Patients who seek EBOO are often looking for advanced wellness therapies that may complement a comprehensive health optimization strategy.

Individuals interested in EBOO frequently have goals such as:

  • Supporting overall wellness and vitality
  • Supporting healthy circulation and oxygen utilization
  • Supporting resilience and recovery
  • Supporting healthy immune system function
  • Complementing nutrition, lifestyle, and wellness programs
  • Pursuing proactive approaches to long-term health and wellness

Because every individual is unique, EBOO is typically incorporated into a broader personalized wellness plan developed in consultation with a qualified healthcare provider.

Understanding the EBOO System

One feature that distinguishes EBOO from many wellness therapies is its use of a specialized closed-loop circulation system.

During treatment, blood remains within a controlled extracorporeal circuit and is continuously monitored throughout the procedure. The system is designed to facilitate oxygenation, ozone administration, and filtration while maintaining a controlled treatment environment under physician supervision.

This advanced technology allows practitioners to incorporate EBOO as part of a comprehensive integrative wellness program tailored to the patient's needs.

EBOO and Ozone Therapy

One aspect of EBOO that often attracts attention is its incorporation of medical-grade ozone.

Ozone is a highly energized form of oxygen that has been studied for decades in various international medical and wellness settings. In EBOO procedures, ozone is administered according to specific protocols within the extracorporeal circulation system.

Practitioners who utilize ozone-based therapies generally view them as part of a broader wellness approach aimed at supporting physiological balance and overall health.

Patients should understand that ozone therapy remains an area of ongoing research and that clinical practices and regulatory environments may vary.

Dr. Monhollon was able to determine I had Lyme’s Disease as well as several infections and parasites. They drew my blood and sent it to Vibrant Labs. After a few weeks, the blood work returned describing the strains of Lymes and the co-infections that made me so sick. Dr Monhollon explained that they didn’t sell ‘packages’ and we were able to afford all the treatments he recommended. I immediately began infusions to strengthen me and blood was drawn for my first SOT. Since it takes a while for it to come back from Greece, they used this time for several EBOO treatments that made such a difference. That was my turning point. I went pleasure shopping for the first time and had hope for the first time.

I had a total of 3 SOT’s along with the EBOO’s. By April I was feeling really good.

Now it is mid-November and I feel like a new person. I do many physical activities now on a regular basis and haven’t had a nap in months. My husband can’t keep up with me and he hasn’t had to cook, clean or grocery shop since last spring! We couldn’t be more happy !!!

When I first arrived at Florida Integrative Medical Center I was hopeless. Now I have my life back!

Thanks for all of the meticulous expert care I received. All the staff was so friendly and supportive. I just can’t thank them enough. You will always have a special place in my heart.

 Linda

Lori B, Former Lyme Warrior

How Is EBOO Different from Other Ozone Therapies?

Many integrative medicine practices offer several forms of ozone therapy.

These may include:

Major Autohemotherapy (MAH)

A procedure in which a small amount of blood is withdrawn, exposed to ozone, and then reinfused.

UBI with Ozone

Ultraviolet Blood Irradiation combined with ozone protocols under physician supervision.

10-Pass Ozone Therapy

A protocol involving multiple cycles of blood withdrawal and reinfusion during a single session.

Of these alternatives FLIMC offers UBI with Ozone and 10-Pass Ozone.

EBOO

Unlike these approaches, EBOO continuously circulates blood through a specialized extracorporeal system throughout the procedure, allowing larger blood volumes to be processed during a treatment session.

Because of its unique technology, EBOO is often considered one of the most advanced ozone-based wellness therapies available in integrative medicine settings.

What Can Patients Expect During an EBOO Session?

The treatment experience may vary based on individual protocols and physician recommendations.

Generally, patients can expect:

  • A consultation and medical evaluation
  • Intravenous access placement
  • Continuous monitoring throughout the procedure
  • A treatment session that may last several hours
  • Post-treatment recommendations tailored to their wellness goals

Many patients choose to relax, read, listen to music, or work remotely during treatment.

EBOO Therapy at Florida Integrative Medical Center

At Florida Integrative Medical Center, EBOO therapy is offered as part of a personalized, physician-directed approach to health and wellness. Under the leadership of Medical Director Dr. John Monhollon, FLIMC was among the earliest medical practices in the United States to incorporate EBOO into patient care. Dr. Monhollon was one of the first physicians in the country to offer the therapy, providing him with years of clinical experience using EBOO as part of individualized wellness programs.

Every patient begins with a comprehensive evaluation that considers medical history, current health concerns, laboratory findings, wellness goals, and overall clinical presentation before therapy recommendations are made.

 

Dr. John Monhollon at Florida Integrative Medical Center

Dr. Monhollon is a board-certified family medicine physician with more than 25 years of clinical experience in integrative and functional medicine. In addition to his extensive medical background, he has completed advanced training in Lyme disease and tick-borne illness management through the International Lyme and Associated Diseases Society (ILADS) and has served as a physician mentor for other healthcare providers pursuing advanced Lyme-focused education.

At FLIMC, EBOO is not viewed as a stand-alone therapy. When appropriate, it may be incorporated into a broader physician-directed wellness strategy that can include advanced diagnostic testing, IV nutrient therapies, ozone-based therapies, lifestyle recommendations, and other personalized wellness services. Our goal is to help patients better understand their health and develop individualized plans that support long-term wellness and quality of life.

Because every patient is unique, treatment recommendations are always based on individual circumstances and determined through consultation with our medical team.

Is EBOO Right for Everyone?

As with any medical or wellness procedure, EBOO may not be appropriate for every individual.

A thorough consultation with a qualified healthcare provider is essential to determine whether the therapy aligns with a patient's health history, wellness goals, and individualized care plan.

Factors such as current medical conditions, medications, and overall health status should always be reviewed before beginning treatment

A Personalized Approach to Wellness

At Florida Integrative Medical Center (FLIMC), EBOO is offered as part of a comprehensive, physician-guided wellness program designed around each patient's unique needs and goals.

Rather than focusing on symptoms alone, our approach emphasizes understanding the broader picture of health through personalized consultations, advanced diagnostics, lifestyle guidance, and supportive therapies.

Patients interested in learning more about EBOO are encouraged to schedule a consultation to discuss whether this advanced wellness therapy may be appropriate as part of their individualized care plan

Important Notice

EBOO is not intended to diagnose, treat, cure, or prevent any disease. Individual experiences may vary. Patients should consult with a qualified healthcare professional regarding any medical concerns and whether EBOO is appropriate for their individual circumstances.

Frequently Asked Questions

What is EBOO therapy?

EBOO stands for Extracorporeal Blood Oxygenation and Ozonation. It is an advanced wellness therapy that circulates blood through a specialized extracorporeal system where it is oxygenated, exposed to medical-grade ozone according to established protocols, and passed through filtration components before being returned to the body.

How does EBOO work?

During an EBOO session, blood circulates through a closed-loop extracorporeal system designed for oxygenation, ozone administration, and filtration. The procedure is performed under medical supervision as part of an individualized wellness plan.

How is EBOO different from other ozone therapies?

Unlike some ozone-based therapies that treat smaller amounts of blood intermittently, EBOO continuously circulates blood through an extracorporeal system throughout the treatment session, allowing larger blood volumes to be processed.

How long does an EBOO session take?

Treatment times vary depending on the protocol used and the individual's care plan. Most sessions take several hours and include physician oversight and monitoring by trained medical staff.

What can patients expect during an EBOO session?

Patients typically receive a consultation and evaluation prior to treatment. During the session, blood circulates through the EBOO system while patients relax, read, work remotely, or listen to music. Treatment recommendations are individualized based on health history and wellness goals.

Is EBOO right for everyone?

No. EBOO may not be appropriate for every individual. A consultation with a qualified healthcare provider is necessary to determine whether the therapy is appropriate based on medical history, current health status, medications, and wellness objectives.

Is EBOO offered under physician supervision?

Yes. At Florida Integrative Medical Center, EBOO is provided under the direction of Dr. John Monhollon, MD and the FLIMC medical team as part of a personalized wellness program.

Can EBOO be combined with other wellness therapies?

Depending on individual circumstances, EBOO may be incorporated into a broader wellness strategy that can include IV nutrient therapies, ozone-based therapies, advanced diagnostic testing, lifestyle recommendations, and other personalized wellness services.