Immune Support Therapy is an autologous process that involves the harvesting of peripheral blood Mononuclear cells from the patient’s own blood by a process called Leukopheresis. The cells are then cultured in the specialized and sophisticated laboratory in the presence of immune stimulatory agents (cytokines) and matured into dendritic cells by exposing them to the patient’s own inactivated tumor cells or with certain tumor specific proteins.
Matured dendritic cells are infused through IV to the patient to boost and fortify the immune system of the patient. It provides necessary impetus the body requires to fight back the cancer.
The heart of the dendritic cell process is the presentation of the immature dendritic cells with cancer specific tumor cells. Each cancer tumor has certain proteins that are phagocytosed by the dendritic cells and the Phagocytosed peptides are then presented on the surface of the dendritic cells for the activation and proliferation of the T cells. The T cells proliferate and secrete certain cytokines that act on the cancer cells. It is different from the conventional therapeutic modalities like surgery, chemotherapy and radiation therapy, as it is highly customised and tailor-made for individual patients and it amplifies the patient’s natural body defense mechanism.
WHAT KIND OF CANCERS CAN BE TREATED WITH IMMUNE SUPPORT THERAPY?
Theoretically, all solid cancers can be treated by dendritic cells. To date, therapeutic benefit has been documented in B cell lymphoma, myeloma, melanoma, head and neck, prostate cancer, colon cancer, ovarian cancer, breast cancer, and renal cell cancer amongst others.
AT WHAT CANCER STAGE SHOULD A PATIENT CONSIDER IMMUNE SUPPORT THERAPY?
The patient can consider Immune Support Therapy at any stage of the cancer.
HOW EFFECTIVE IS IMMUNE SUPPORT THERAPY?
Responses have generally been promising as it is an autologous process; it reduces cancer morbidity and improves the quality of life. Depending on the type of cancer and the functional status of patients the response may differ from patient to patient.
For more information about our IST treatment, please contact our office at (941) 955-6220
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