RGCC Testing

Circulating Tumor Cells (CTCs) are cells that have detached from the primary tumor and flow into the blood or lymphatic circulation creating a secondary tumor. Despite their rare population, these cells exhibit metastatic attributes and are related to cancer progression.

The R.G.C.C test is a test for patient’s seeking personalised cancer testing where it has the ability to:
-Detect early signs of developing cancer
-Help monitoring existing cancers
-Produce an individual profile of chemotherapeutic drugs and natural substances that can be used to achieve the best treatment outcomes.


Testing options available: 


Oncocount: Provides information on the presence and the concentration of Circulating Tumor Cells (CTC’s). It enumerates only the progenitor cells that are relevant to potent relapse and recurrence of the disease.


Oncotrace: Provides information about the presence of Circulating Tumor Cells (CTC’s), Their concentration and immunophenotype, which may help identify their origin.


Oncotrail: Provides information about the presence of Circulating Tumor Cells (CTC’s) and their concentration and immunophenotype for specific types of malignancies. This test is a tailor-made test for specific type of malignancies such as breast cancer (Oncotrail R.G.C.C. for Breast), Prostate (Oncotrail for Prostate), Sarcoma etc. This test includes only markers relevant for a specific type of malignancy which make the test a good tool for follow up control.


Immune Frame: Profile of humoral and cellular immunity and cachexia. This test is focusing on the status of the immune system and immunity.


Onconomics Plus: Provides information about the efficacy of specific drugs on the cancer cells derived from a single patient. The method incorporates two procedures (epigenetic analysis and viability assays) to validate the data. The efficacy of natural biological substances or extracts on cancer cells is also referred to. The assessment is based on three methods: the direct cytotoxic effect, stimulation of the immune system and the inhibition of proliferative signals in the cancer cells.


Onconomics Extracts: Provides information about the efficacy of natural biological substances or extracts on cancer cells. The assessment is based on three methods: the direct cytotoxic effect, stimulation of the immune system and the inhibition of proliferative signals in the cancer cells.


Chemo SNP: SNPs analysis of cytostatic drugs. Pharmacogenomics is the science that examines the inherited variations in genes that dictate drug response and explores the ways these variations can be used to predict whether a patient will have a good response to a drug, a bad response to a drug or no response at all. 
Single Nucleotide Polymorphisms (SNPs) aare DNA sequence variations that can affect how humans develop disease or respond to chemicals, drugs and other agents. 
ChemoSNiP includes the study of SNPs of genes that are included in metabolism/detoxification of cytostatic or targeted drugs which are used as cancer therapy.

Metastat: Markers on CTCs that point out the potent organ for relapse. 
From literature, numerous markers are associated with specific tumor organ metastases.
The Metastat test is a collection of specific markers that are detected on specific organs. 
Cells of the primary tumor that have the ability to metastasize will express specific genes and proteins according to the organ that will metastasize, and that is given by the genetic information.

Immune Frame: Profile of humoral and cellular immunity and cachexia. This test is focusing on the status of the immune system and immunity.

aCGH: Unbalanced chromosomal abnormalities might lead to different genetic disorders as well as cancer. Array CGH can be used to identify imbalances in an entire genome with higher resolution than traditional microscopic methods. The above aberrations could be correlated with genome regions that might be useful in identification of the primary origin of tumor.


Click here for more information or call our office at (941) 955-6220 and speak to one of our expert staff members today

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